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Mol Pharmacol 65:10081015 Had-Aissouni L (2012) Toward a new role for plasma membrane sodium-dependent glutamate transporters of astrocytes: maintenance of antioxidant defenses beyond extracellular glutamate clearance

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For example, poorly digested proteins can be fermented by bacteria in the gut to form amino acid-derived metabolites, such as branched-chain fatty acids (BCFAs) and ammonia, which can have toxic impacts on the intestinal tissue, contributing to leaky gut